HDL Raising Drugs Probably Won’t Work But This Might

A new study offers important new insights into the protective role of HDL cholesterol (the “good” cholesterol) against cardiovascular disease. Earlier studies with drugs that increase HDL levels, including niacin and CETP inhibitors, have not shown benefit. The new study suggests that simply increasing HDL levels isn’t the way to go. Instead, cholesterol efflux, the ability of HDL to remove cholesterol from cells, part of the process called reverse cholesterol transport, appears to be the key. The results were presented today by Anand Rohatgi at the American Heart Association meeting in Chicago and published simultaneously in the New England Journal of Medicine. The investigators More…
Source: CardioBrief - Category: Cardiology Authors: Tags: Prevention, Epidemiology & Outcomes cholesterol efflux HDL reverse cholesterol transport Source Type: blogs