Patient-specific changes in motor network functional connectivity after brain stimulation in perinatal stroke

Introduction: Most hemiparetic cerebral palsy is caused by perinatal stroke resulting in lifelong motor disability. As a focal injury of defined timing in an otherwise healthy brain, perinatal stroke is an ideal human model of developmental neuroplasticity. Evidence shows that intensive rehabilitation paired with non-invasive brain stimulation can improve motor function. However, given large individual variability in plasticity, group statistics may not capture important patient-centred changes.

Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation - January 22, 2019 Category: Neurology Authors: H. Carlson, A. Kirton Source Type: research