Successful lung transplantation in a patient with Niemann ‒Pick disease
It is with great interest that we read the case report by Mannem and colleagues.1 Unfortunately, their patient died within 30 days of lung transplantation from acute lung injury due to a pro-inflammatory state caused by flooded recipient-derived abnormal macrophage in the lungs. The authors concluded that transplanting patients with an orphan lung condition like Niemann ‒Pick disease carries a higher risk of complications, as the effect of the underlying disease on the post-operative course is difficult to predict.
Source: The Journal of Heart and Lung Transplantation - Category: Transplant Surgery Authors: Feihong Ding, Atul C. Mehta, A. Valeria Arrossi Tags: CASE ANECDOTES, COMMENTS AND OPINIONS Source Type: research
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