Memantine potentiates cytarabine-induced cell death of acute leukemia correlating with inhibition of Kv1.3 potassium channels, AKT and ERK1/2 signaling

Treatment of acute leukemia is challenging and long-lasting remissions are difficult to induce. Innovative therapy approaches aim to complement standard chemotherapy to improve drug efficacy and decrease toxic...

Source: Cell Communication and Signaling - January 16, 2019 Category: Molecular Biology Authors: Theresa Lowinus, Florian H. Heidel, Tanima Bose, Subbaiah Chary Nimmagadda, Tina Schn öder, Clemens Cammann, Ingo Schmitz, Ulrike Seifert, Thomas Fischer, Burkhart Schraven and Ursula Bommhardt Tags: Research Source Type: research