Protection of Chickens Against Fowl Cholera by Supernatant Proteins of Pasteurella Multocida Cultured in an Iron- Restricted Medium.

Protection of Chickens Against Fowl Cholera by Supernatant Proteins of Pasteurella Multocida Cultured in an Iron- Restricted Medium. Avian Pathol. 2019 Jan 14;:1-27 Authors: Luo Q, Kong L, Dong J, Zhang T, Wang H, Zhang R, Lu Q, Chen H, Shao H, Jin M Abstract Pasteurella multocida (P. multocida), a causative agent of fowl cholera, is an important pathogen in the poultry industry. In the present study, we found that the inactivated vaccine of P. multocida grown in an iron-restricted medium provided better protection than that grown in normal medium. Thus, we adopted a comparative proteomics approach, by using two-dimensional gel electrophoresis (2-DE), coupled with matrix-assisted laser desorption/ionization time of flight mass spectrometry (MALDI-TOF/TOF MS), to profile the supernatant proteins associated with P. multocida under both conditions. Eleven upregulated proteins were identified, including aspartate ammonia-lyase (AspA), diacylglycerol kinase (DgK), 30S ribosomal protein S6 (RpsF), and eight outer membrane proteins (OMPs). To further characterize the three novel supernatant proteins identified under iron-restricted conditions, the AspA, DgK and RpsF proteins were expressed and purified, and used as immunogens to vaccinate chickens. The results showed that AspA, DgK and RpsF proteins developed 80.0%, 66.7%, and 80.0% immunity, respectively. These data indicated that the three novel proteins identified in the supernatant of the culture media migh...
Source: Avian Pathology - Category: Pathology Authors: Tags: Avian Pathol Source Type: research

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Conclusion: Uganda successfully developed a national multi-hazard emergency preparedness and response plan using the preparedness logic model. The plan is now ready for implementation by the Uganda MoH and partners. PMID: 31526179 [PubMed - in process]
Source: Global Health Action - Category: International Medicine & Public Health Tags: Glob Health Action Source Type: research
Publication date: Available online 28 June 2019Source: Microbes and InfectionAuthor(s): Jean-Marc Cavaillon, Sandra LegoutAbstractThe Institut Pasteur was created thanks to worldwide generosity with the aim to welcome and treat rabies patients, to provide a place for scientific research and to offer new teaching programs in microbiology. Louis Pasteur invited his main collaborators, who had accompanied him during his previous investigations at École Normale Supérieure, to join him in his new institute. They contributed to the principle discoveries of Pasteur, such as the fight against spontaneous generation, ...
Source: Microbes and Infection - Category: Infectious Diseases Source Type: research
Publication date: Available online 17 July 2018Source: Veterinary MicrobiologyAuthor(s): Briana Petruzzi, Rami A. Dalloul, Tanya LaRoith, Nicholas P. Evans, F. William Pierson, Thomas J. InzanaAbstractPasteurella multocida is the causative agent of avian cholera, an important economic and ecological disease that can present as a peracute, acute, chronic, or asymptomatic infection. Acute avian cholera is associated with encapsulated P. multocida, while chronic and asymptomatic cases of avian cholera may be associated with capsule-deficient P. multocida isolates. We hypothesize that biofilm formation is important for chronic...
Source: Veterinary Microbiology - Category: Veterinary Research Source Type: research
This report describes the evaluation of two avian cholera outbreaks in two canary (Serinus canaria) aviaries, located in southern Brazil. The first outbreak had its onset after a thermal inversion, when the canaries exhibited clinical signs that included dyspnea, conjunctivitis, cyanosis, and death. The clinical progression of the disease, on average, lasted two days, leading to a 40% loss of birds within the aviary. In the second outbreak the canaries also went through a thermal inversion, ending up with several cases of sudden death (60% of mortality) in a period of 24 hours.
Source: Journal of Exotic Pet Medicine - Category: Veterinary Research Authors: Tags: Case Report Source Type: research
This report describes the evaluation of 2 avian cholera outbreaks in two canary (Serinus canaria) aviaries located in southern Brazil. The first outbreak had its onset after a thermal inversion, when the canaries exhibited clinical signs that included dyspnea, conjunctivitis, cyanosis, and death. The clinical progression of the disease, on average, lasted 2 days, and lead to a 40% loss of birds within the aviary. In the second outbreak the canaries also went through a thermal inversion, ending up with several cases of sudden death (60% of mortality) in a period of 24 hours.
Source: Journal of Exotic Pet Medicine - Category: Veterinary Research Authors: Tags: Case Report Source Type: research
This report describes the evaluation of two avian cholera outbreaks in two canary (Serinus canaria) aviaries, located in southern Brazil. The first outbreak had its onset after a thermal inversion, when the canaries exhibited clinical signs that included dyspnea, conjunctivitis, cyanosis, and death. The clinical progression of the disease, on average, lasted two days, leading to a 40% loss of birds within the aviary. In the second outbreak the canaries also went through a thermal inversion, ending up with several cases of sudden death (60% of mortality) in a period of 24 hours.
Source: Journal of Exotic Pet Medicine - Category: Veterinary Research Authors: Tags: Case Report Source Type: research
Pasteurella multocida causes fowl cholera (FC), a contagious bacterial disease of domestic and wild avian species. It is a Gram negative coccobacilli causing acute highly fatal septicemia with high morbidity and mortality rate. Control of fowl cholera is primarily performed by good management practice and vaccination in areas where disease is endemic. For a quality vaccine, high density grow...
Source: African Journal of Microbiology Research - Category: Microbiology Source Type: research
This study shows that CTB is easily taken up by nerve terminals which innervate the biceps brachii muscle of the pigeon and that cerebral motor neurons controlling the biceps brachii muscle are located in the hyperpallium apicale.
Source: Anatomia, Histologia, Embryologia: Journal of Veterinary Medicine Series C - Category: Veterinary Research Authors: Tags: ORIGINAL ARTICLE Source Type: research
Abstract Biological invasions are a major driver of biodiversity loss, but no study has described the scope of threats to bats (Chiroptera) by invasive species. We reviewed the literature for negative effects of invasive species to bats and summarised threats according to four categories: predation, disease, competition, and indirect interactions. We identified threats of 37 invasive species to 40 bat species. Ten bat species were threatened by more than one invasion pathway. About 38 percent of cases are speculative and 18 percent circumstantial, many attributed to overlapping ranges, and most accounts do not quantify...
Source: Mammal Review - Category: Zoology Authors: Tags: Review Source Type: research
This article is protected by copyright. All rights reserved. The projections of the nTTD were examined in a songbird, using in vivo injections of sensitive neural tracers. The results revealed a high degree of intra‐trigeminal connectivity (blue) and demonstrated ascending projections to the contralateral thalamus (red), similar to those in mammals.
Source: The Journal of Comparative Neurology - Category: Neurology Authors: Tags: Research Article Source Type: research
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