Ambulance Equipment Contaminated With MRSA Ambulance Equipment Contaminated With MRSA

Ambulance oxygen tanks are likely to carry methicillin-resistant Staphylococcus aureus (MRSA), a small U.S. study suggests, pointing to the need for regular disinfection of medical equipment.Reuters Health Information
Source: Medscape Medical News Headlines - Category: Consumer Health News Tags: Infectious Diseases News Source Type: news

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We describe the design and preclinical development of AB-SA01, a fixed-composition bacteriophage product intended to treat Staphylococcus aureus infections. AB-SA01 contains three naturally occurring, obligately lytic myoviruses related to Staphylococcus phage K. AB-SA01 component phages have been sequenced and contain no identifiable bacterial virulence or antibiotic resistance genes. In vitro, AB-SA01 killed 94.5% of 401 clinical Staphylococcus aureus isolates, including methicillin-resistant and vancomycin-intermediate ones for a total of 95% of the 205 known multidrug-resistant isolates. The spontaneous frequency of re...
Source: Viruses - Category: Virology Authors: Tags: Article Source Type: research
Methicillin resistant Staphylococcus aureus (MRSA) remains an important cause of healthcare-associated infections. Here, we describe the development of methicillin-resistant isolates among nosocomial Staphylococcus aureus (SA) infections in Germany between 2007 and 2016.
Source: Journal of Infection - Category: Infectious Diseases Authors: Source Type: research
Cellulitis commonly causes patient emergency department visits and hospital admits in the United States. Since the emergence of Methicillin-resistant Staphylococcus aureus (MRSA) infections, many practitioners are reluctant to take a conservative approach to treating cellulitis. Some studies have shown an incidence as high as 204 cases per 100,000 people for emergency department cellulitis visits [1,2]. The expense of these visits is vast and places avoidable strain on health care dollars. The average hospital stay (5  days) for patients treated for cellulitis costs roughly $7341 [1,3].
Source: The American Journal of Emergency Medicine - Category: Emergency Medicine Authors: Source Type: research
Methicillin-resistant Staphylococcus aureus (MRSA) infection is caused by S aureus bacteria and can be fatal. There are 2 major strains of MRSA: hospital-acquired (HA) MRSA and community-acquired (CA) MRSA. HA-MRSA includes cases in which the patient has had a current or recent hospitalization, receives dialysis, resides in a long-term care facility, or has had recent antibiotic use.
Source: Medscape Today Headlines - Category: Consumer Health News Tags: Resource Center Source Type: news
Abstract In humans, the occurrence of bacterial communities in the form of biofilm is considered as a major intrinsic factor accountable for a variety of stubborn infections. Staphylococcus aureus and S. epidermidis have gained considerable attention in clinical settings owing to the formation of intractable and long-lasting biofilms in medical device. The current study has been designed to explain the biofilm inhibitory efficacy of geraniol and cefotaxime combination (GCC) against S. epidermidis and methicillin-resistant S. aureus (MRSA). Biofilm biomass quantification assay was performed to evaluate the antibiof...
Source: Food and Chemical Toxicology - Category: Food Science Authors: Tags: Food Chem Toxicol Source Type: research
Publication date: Available online 12 January 2019Source: International Journal of PharmaceuticsAuthor(s): Daniel Hassan, Calvin A. Omolo, Ramesh Gannimani, Ayman Y. Waddad, Chunderika Mocktar, Sanjeev Rambharose, Nikhil Agrawal, Thirumala GovenderAbstractThe development of novel antibiotic systems is needed to address the methicillin-resistant Staphylococcus aureus (MRSA) infections. The aim of the study was to explore the novel nanoplex delivery method for vancomycin (VCM) against MRSA using dextran sulfate sodium salt (DXT) as a polyelectrolyte complexing agent. Nanoplexes were formulated by the self-assembling amphiphi...
Source: International Journal of Pharmaceutics - Category: Drugs & Pharmacology Source Type: research
n Ryu Staphylococcus aureus is one of the notable human pathogens that can be easily encountered in both dietary and clinical surroundings. Among various countermeasures, bacteriophage therapy is recognized as an alternative method for resolving the issue of antibiotic resistance. In the current study, bacteriophage CSA13 was isolated from a chicken, and subsequently, its morphology, physiology, and genomics were characterized. This Podoviridae phage displayed an extended host inhibition effect of up to 23 hours of persistence. Its broad host spectrum included methicillin susceptible S. aureus (MSSA), methicillin re...
Source: Viruses - Category: Virology Authors: Tags: Article Source Type: research
ConclusionsA major MRSA lineage, CC8-ST239-MRSA-SCCmec type III-spa type t037, is noted among bacteremic MRSA isolates. No disease-specific virulent genes can be identified.
Source: Journal of Microbiology, Immunology and Infection - Category: Microbiology Source Type: research
ConclusionsThese findings revealed that ST9-t1939-agrI was the main genotype of MSSA, whilst ST1-SCCmecI-t1939-agrI was the main genotype of MRSA from dairy cows. More significantly, a novel ST (STX) was identified for the first time. The majority of SA strains from dairy cows were multidrug-resistant and carried multiple virulence genes, posing a potential public-health risk.
Source: Journal of Global Antimicrobial Resistance - Category: Infectious Diseases Source Type: research
Publication date: Available online 9 January 2019Source: Veterinary MicrobiologyAuthor(s): Constanze Ernst, Alexander Bartel, Johannes Wilhelmus Elferink, Jennifer Huhn, Erik Eschbach, Kirsten Schönfeld, Andrea T. Feßler, Boris Oberheitmann, Stefan SchwarzAbstractMolecular methods offer fast, safe and cost-efficient detection of pathogenic bacteria, including methicillin-resistant Staphylococcus aureus (MRSA). These tests depend on a rapid extraction of bacterial DNA. The aim of this study was to compare an optimized DNA extraction and purification protocol for MRSA using magnetic nanoparticles with the original...
Source: Veterinary Microbiology - Category: Veterinary Research Source Type: research
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