Nox4 and soluble epoxide hydrolase synergistically mediate homocysteine-induced inflammation in vascular smooth muscle cells.

CONCLUSIONS: The inflammatory response induced by homocysteine in VSMCs was accompanied by Nox4 and sEH upregulation. Nox4 and soluble epoxide hydrolase synergistically contribute to homocysteine-induced inflammation.
PMID: 30610956 [PubMed - as supplied by publisher]

Source: Vascular Pharmacology - January 2, 2019 Category: Drugs & Pharmacology Authors: Liu X, Qin Z, Liu C, Song M, Luo X, Zhao H, Qian D, Chen J, Huang L Tags: Vascul Pharmacol Source Type: research