4-Phenylbutyric Acid Attenuates Endoplasmic Reticulum Stress-Mediated Intestinal Epithelial Cell Apoptosis in Rats with Severe Acute Pancreatitis

ConclusionsERS may be considered a predominant pathway, which is involved in the apoptosis of IECs during SAP. Furthermore, 4-PBA protects IECs against apoptosis in STC-induced SAP by attenuating the severity of ERS.

http://link.springer.com/10.1007/s10620-018-5437-1

Source: Digestive Diseases and Sciences - January 4, 2019 Category: Gastroenterology Source Type: research