Purinergic receptors in neurogenic processes.

Purinergic receptors in neurogenic processes. Brain Res Bull. 2018 Dec 26;: Authors: Ribeiro DE, Glaser T, Oliveira-Giacomelli Á, Ulrich H Abstract Neurogenesis is a process of generating functional neurons which occurs during embryonic and adult stages in mammals. While neurogenesis during development phase is characterized by intensive proliferation activity in all regions of the brain to form the architecture and neural function of the nervous system, adult neurogenesis occurs with less intensity, in only two brain regions, and is involved in the maintenance of neurogenic niches, local repairmen, memory and emotional functions in the hippocampus. Taking such differences into account, the understanding of molecular mechanisms involved in cell differentiation in developmental stages and maintenance of the nervous system is an important research target. Although embryonic and adult neurogenesis presents several differences, signaling through purinergic receptors participates in this process throughout life. PMID: 30593881 [PubMed - as supplied by publisher]
Source: Brain Research Bulletin - Category: Neurology Authors: Tags: Brain Res Bull Source Type: research