In vitro effects of benzalkonium chloride and prostaglandins on human meibomian gland epithelial cells.

CONCLUSIONS: BAC showed cytotoxic effects on HMGECs starting with a concentration of 0.1μg/ml. The combination of BAC and prostaglandin-analogs might have a synergistic effect which results in higher toxicity than BAC alone. Unpreserved eye drops and eye drops preserved with Polyquaternium-1 are less damaging to HMGECs. PMID: 30580056 [PubMed - as supplied by publisher]
Source: Annals of Anatomy - Category: Anatomy Authors: Tags: Ann Anat Source Type: research