Increased Accuracy After Adjustment of Spirometry Threshold for Diagnosing COPD Based on Pre-Bronchodilator FEV1/FVC.
Increased Accuracy After Adjustment of Spirometry Threshold for Diagnosing COPD Based on Pre-Bronchodilator FEV1/FVC. Respir Care. 2019 Jan;64(1):85-90 Authors: Kronborg T, Hangaard S, Cichosz SL, Hejlesen O Abstract BACKGROUND: COPD is a leading cause of morbidity and mortality worldwide. Spirometry is the most common lung function test for diagnosing COPD with a post-bronchodilator FEV1/FVC
CONCLUSION: The increase of miR-7 methylation levels experienced by COPD patients occurs mainly at the expense of the emphysema phenotype, which might contribute to explain the higher incidence of lung cancer in these patients. PMID: 31780284 [PubMed - as supplied by publisher]
Conclusion: Frailty is common in CRD patients referred to PR and this data suggests pulmonary rehabilitation is effective in CRD irrespective of frailty status.Reference:1 Mittal J Prim Care Community Health 2016;7(1)10-15
Conclusion: Influenza with CLD is associated with longer length of stay in under 50’s compared to non-CLD. Readmission and mortality were higher in CLD patients.Table 1.AgeNo of patientsPts with CLDsMean Hospital stay (Days)Pts without CLDsMean Hospital Stay(Days)18-30417(17%)11.234(83%)1.231-505818(31%)5.240(69%)2.651-6511143(39%)8.168(61%)7.566-7513956(40%)9.683(60%)11.576-8516352(32%)14111(68%)15.586-9915642(27%)19.5114(73%)20.2
Conclusion: The determinants of suitability for HD-ICS prescription in primary care records are inconsistently recorded, difficult to identify and challenging to apply.
Conclusion: The vast majority of patients gained a clinically important improvement. Symptom burden may be more important for selecting patients for PR than diagnosis.
Conclusion: In patients with COPD, we considered that attention to the onset of LC should be paid regardless of the background factors. In patients with COPD, it was effective to perform chest CT once a year for early detection and treatment of LC.
Conclusion: SpiroNose data obtained by tidal breaths and VC manoeuvres are not interchangeable. VC manoeuvres provide the highest accuracies in the cross comparison of controls and asthma, COPD and lung cancer patients.
Background: Airborne particulate matter (PM) is a leading cause of mortality and respiratory morbidity, associated with asthma, COPD, lung cancer, and IPF. Effects of inhaled PM may depend on PM chemistry, and thus source. Ships, dockside and freight activities are major sources of PM in port cities, but the chemistry and toxicology of such PM is poorly understood; shoreside sources receive little attention, especially the unregulated ultrafine (UF) fraction.Aim: To determine the chemical and toxicological properties of port-generated PM.Methods: Size-fractionated airborne PM (diameter 10-2.5µm (coarse[C]), 2.5-0.1µm (fine[F]),
Conclusions: In our sample, expensive SC medication was one of the main barriers, since in Portugal varenicline is the only reimbursed prescription drug to SC. Higher levels of anxiety and choosing the wrong time to quit hindered the success of SC. Handing out self-reported questionnaires is a possible way to identify barriers to SC and improve the success of SC programs.
Aim: To determine the characteristics of chronic lung diseases in patients with mycobacterioses caused by slowly growing nontuberculous mycobacteria (NTM).We studied 51 patients with pulmonary mycobacterioses caused by slowly growing NTM; the average age was 54.1±0.3 yrs; disease duration was 19.5±0.5 months. In all patients the diagnosis was microbiologically verified. Out of them 25 (49%) were infected with M. avium, 21.5% – M. intracellulare, 9.8% – M. kansasii, 5.8% – M. xenopi, 3.9% – M. gordonae, 3.9% – M. lentiflavum. Four patients were co-infected with M. avium + M. intra...