FDG-avid presacral soft tissue mass in previously treated rectal cancer: Diagnostic outcome and additional value of MRI, including diffusion-weighted imaging

ConclusionsFDG-PET/CT has a poor PPV for locally recurrent rectal cancer in the presacral space. The observation of air in the FDG-avid presacral lesion and additional MRI assessment are diagnostically helpful, without a significant additional value of DWI.
Source: European Journal of Surgical Oncology (EJSO) - Category: Surgery Source Type: research

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The role of hybrid imaging using 18F-fluoro-2-deoxy-D-glucose positron-emission tomography (FDG-PET), computed tomography (CT) and magnetic resonance imaging (MRI) to improve preoperative evaluation of rectal can...
Source: Cancer Imaging - Category: Radiology Authors: Tags: Research article Source Type: research
Conclusions: 3D-HDR-BT achieves favorable clinical outcomes with mild late toxicity in patients with locally rNPC. Introduction Nasopharyngeal carcinoma (NPC), a tumor of epithelial origin, is a malignant disease of the head and neck common in southern China, especially in Guangdong province (1). As a result of advances in modern imaging and irradiation techniques, the 5-year overall survival (OS) of patients with newly diagnosed NPC without metastasis has reached 75% after external beam radiotherapy (EBRT) in Asia (2, 3). However, local recurrence, which occurs in 18–40% of patients, remains a major reason for...
Source: Frontiers in Oncology - Category: Cancer & Oncology Source Type: research
Publication date: Available online 12 March 2019Source: Journal of Visceral SurgeryAuthor(s): Y. Eid, B. Menahem, V. Bouvier, G. Lebreton, A. Thobie, C. Bazille, M. Finochi, A. Fohlen, M.P. Galais, B. Dupont, J. Lubrano, O. Dejardin, R. Morello, A. AlvesSummaryIntroductionIn 2006 under the supervision of the French health authorities (HAS), recommendations for clinical practice (RCP) in the management of rectal cancers were first published. The primary objective of this study was to assess the impact of these guidelines on multidisciplinary management in terms of therapeutic strategies based on disease staging and quality ...
Source: Journal of Visceral Surgery - Category: Surgery Source Type: research
Authors: Nardone V, Reginelli A, Scala F, Carbone SF, Mazzei MA, Sebaste L, Carfagno T, Battaglia G, Pastina P, Correale P, Tini P, Pellino G, Cappabianca S, Pirtoli L Abstract Background: We hypothesized that texture analysis (TA) from the preoperative MRI can predict early disease progression (ePD), defined as the percentage of patients who relapsed or showed distant metastasis within three months from the radical surgery, in patients with locally advanced rectal cancer (LARC, stage II and III, AJCC) undergoing neoadjuvant chemoradiotherapy (C-RT). Methods: This retrospective monoinstitutional cohort study in...
Source: Gastroenterology Research and Practice - Category: Gastroenterology Tags: Gastroenterol Res Pract Source Type: research
CONCLUSION: Dual-energy CT demonstrated a difference in the mean atomic mass in benign colorectal tumors in comparison to malignant colorectal tumors. PMID: 30764692 [PubMed - as supplied by publisher]
Source: Acta Oncologica - Category: Cancer & Oncology Authors: Tags: Acta Oncol Source Type: research
Discussion: This review will help determine the diagnostic accuracy of CT, MRI, PET, and PET-CT for the diagnosis of patients with LR of rectal cancer. Ethics and dissemination: Ethics approval and patient consent are not required, as this study is a systematic review. PROSPERO registration number: CRD42018104918.
Source: Medicine - Category: Internal Medicine Tags: Research Article: Study Protocol Systematic Review Source Type: research
AbstractBackgroundThe aim of this study was to elucidate the diagnostic value of18F-fluorodeoxyglucose positron emission tomography (PET) –computed tomography (CT) for lateral pelvic lymph node (LPN) metastasis in rectal cancer treated with preoperative chemoradiotherapy (CRT).MethodsEighteen rectal cancer patients with enlarged ( ≥ 8 mm) LPNs were treated with CRT followed by total mesorectal excision with LPN dissection during 2012–2015. After CRT, LPN maximum standard uptake values (SUVmax) were measured using PET/CT and long diameters of LPNs were measured using CT or magnetic resonance imagi...
Source: Techniques in Coloproctology - Category: Surgery Source Type: research
ConclusionIn this region of Ontario, pre‐operative MRI was underutilized, CT reporting of MRF status was low, and when reported sensitivity and specificity of T‐ and N‐category were similar for CT and MRI.
Source: Journal of Surgical Oncology - Category: Cancer & Oncology Authors: Tags: RESEARCH ARTICLE Source Type: research
In conclusion, this combined metabolic approach appears effective in treating advanced TNBC, given this patient’s complete response with a good quality of life.Now, there is one thing that is interesting here. The doses of chemotherapy used were considerably lower thanwhat is usually used, with doses decreased by at least half or more. Does this mean anything? Who knows? cPR rates for TNBC have been reported to range from 20-35%. It could mean the regimen made the chemotherapy more effective, or it could mean that this woman just happened to have a particularly chemosensitive tumor. Even if we take this case report a...
Source: Respectful Insolence - Category: Surgery Authors: Source Type: blogs
In conclusion, this combined metabolic approach appears effective in treating advanced TNBC, given this patient’s complete response with a good quality of life.Now, there is one thing that is interesting here. The doses of chemotherapy used were considerably lower thanwhat is usually used, with doses decreased by at least half or more. Does this mean anything? Who knows? cPR rates for TNBC have been reported to range from 20-35%. It could mean the regimen made the chemotherapy more effective, or it could mean that this woman just happened to have a particularly chemosensitive tumor. Even if we take this case report a...
Source: Respectful Insolence - Category: Surgery Authors: Source Type: blogs
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