ATP-activated decrosslinking and charge-reversal vectors for siRNA delivery and cancer therapy

Conclusion: These results indicated that the ATP-triggered disassembly and charge reversal strategy provided a new way for developing stimuli-responsive siRNA carriers and showed potential for nucleic acid delivery in the treatment of cancer.

Source: Theranostics - December 7, 2018 Category: Molecular Biology Authors: Zhanwei Zhou, Qingyan Zhang, Minghua Zhang, Huipeng Li, Gang Chen, Chenggen Qian, David Oupicky, Minjie Sun Tags: Research Paper Source Type: research