Development of an Accurate and Proactive Immunomodulatory Strategy to Improve Bone Substitute Material-Mediated Osteogenesis and Angiogenesis

Conclusions: Accurate immunomodulation via IL4 delivery significantly enhanced DBM-mediated osteogenesis and angiogenesis via the coordinated involvement of M1 and M2 macrophages, revealing the promise of this accurate and proactive immunomodulatory strategy for developing new bone substitute materials.

Source: Theranostics - December 7, 2018 Category: Molecular Biology Authors: Zhi-wei Zheng, Ya-hong Chen, Ding-yu Wu, Jin-bing Wang, Ming-ming Lv, Xian-song Wang, Jian Sun, Zhi-Yong Zhang Tags: Research Paper Source Type: research