MicroRNA-195 protection against focal cerebral ischemia by targeting CX3CR1.

CONCLUSIONSTaken together, these findings suggest that miR-195 promotes neuronal cell survival against chronic cerebral ischemic damage by inhibiting CX3CR1-mediated neuroinflammation. This indicates that miR-195 may represent a novel target that regulates neuroinflammation and brain injury, thus offering a new treatment strategy for cerebral ischemic disorders. PMID: 30497184 [PubMed - as supplied by publisher]
Source: Journal of Neurosurgery - Category: Neurosurgery Tags: J Neurosurg Source Type: research