Low Prevalence of Human Papilloma Virus in Patients with Breast Cancer, Kerman; Iran

Low Prevalence of Human Papilloma Virus in Patients with Breast Cancer, Kerman; Iran Asian Pac J Cancer Prev. 2018 Nov 29;19(11):3039-3044 Authors: Malekpour Afshar R, Balar N, Mollaei HR, Arabzadeh SA, Iranpour M Abstract Breast cancer is the first of the most important causes of the deaths of women in the world and in Iran. There are various causes and causes of this cancer, one of which has recently been described as a cause of breast cancer, is the human papillomavirus (HPV). The HPV is transmitted through sexual contact and skin lesions. There are more than 100 types of HPV that can influence different parts of the body. Some types of HPV can cause cancer (such as cervical or anal cancer) and others can cause warts (such as genital or plantar warts). To study the risk of HPV infection in Breast Cancer, we managed a Case-Control study in Kerman, southeast of Iran. For this purpose, 98 paraffin blocks of breast cancer and 40 paraffin blocks of fibrocystic as a control were tested for the presence of HPV DNA using Real-Time PCR, and HPV typing was done using INNo-Lippa assay. HPV DNA was detected in 8 out of 98 patients (8.2%), while it was not detected in the control group samples. HPV types 16, 18 were the most common (62.5%) types in positive samples. The prevalence of HPV in patients with breast cancer of Iran is very low and less than other regions of the world, it seems that maybe rout of transmission of HPV in Iran is under ...
Source: Asian Pacific Journal of Cancer Prevention - Category: Cancer & Oncology Tags: Asian Pac J Cancer Prev Source Type: research