Dosimetric evaluation of an atlas-based synthetic CT generation approach for MR-only radiotherapy of pelvis anatomy.
CONCLUSION: We investigated the potential of a multiatlas approach to generate synthetic CT images for the pelvis. Our results demonstrate excellent results in terms of HU value assignment compared to the original CT and dosimetric consistency. PMID: 30474353 [PubMed - as supplied by publisher]
We read with great interest the authors ’ take on pelvic lymph node involvement as detected on Gallium-68-prostate specific membrane antigen (Ga68-PSMA) positron emission tomography (PET) computed tomography (CT) and congratulate them on their possibly practice-changing findings . Till recently, the standard staging investigations fo r a patient with carcinoma prostate would include a CT or magnetic resonance imaging (MRI) of pelvis along with a bone scan; paucity of anatomic abdominal imaging or whole body biologic imaging resulted in the fact that small or early common iliac and lower paraaortic nodal metastases...
In this study of Chinese men with biochemical recurrence, added value for the detection of lesions compatible with sites of PCa was found with68Ga-PSMA-11 PET/CT over conventional imaging. The observed patterns of disease spread may have implications for understanding the biology of early prostate cancer metastasis.
ConclusionSegmentation of prostate cancers is more difficult than other anatomy such as kidney tumors. Less experienced participants appear to under ‐segment models and underestimate the size of prostate tumors. Segmentation of prostate cancer is highly variable even among radiologists, and 3D modeling for clinical use must be performed with caution. Further work to develop a methodology to maximize segmentation accuracy is needed.
CONCLUSION: This first AIRO survey about salvage prostate re-EBRT provides an interesting snapshot and suggests increasing interest in re-EBRT patients in Italy. Consensus about some aspects of patients' selection, the necessity of biopsy, fractionation, and highly selective techniques seems feasible, but other key points such as irradiated volume, dosimetry parameters, and hormonal treatment association need to be clarified. PMID: 32583236 [PubMed - indexed for MEDLINE]
ConclusionThis first AIRO survey about salvage prostate re-EBRT provides an interesting snapshot and suggests increasing interest in re-EBRT patients in Italy. Consensus about some aspects of patients ’ selection, the necessity of biopsy, fractionation, and highly selective techniques seems feasible, but other key points such as irradiated volume, dosimetry parameters, and hormonal treatment association need to be clarified.
This article presents the contribution of the latest advances in these two imaging techniques of prostate cancer and their future developments. PMID: 32620459 [PubMed - as supplied by publisher]
ConclusionsIntegrated [68Ga]PSMA-11 PET/MRI provides a similarly high diagnostic performance for localization of recurrent PC as PET/CT. For the detection of local recurrences [68Ga]PSMA-11 PET/MRI is superior compared with [68Ga]PSMA-11 PET/CT.
We present a case of a 79 year old patient with a medical history of unilateral nerve-sparing radical prostatectomy due to a pT3aN0 (Gleason score 7) prostate carcinoma. Because of slightly elevated prostate specific antigen (PSA) level (0.35ng/dL), a fluorine-18-prostate specific membrane antigen (18F-PSMA)-1007 positron emission tomography/computed tomography (PET/CT) scan was performed, showing no signs of malignant recurrence. However, a moderately PSMA-avid nodular lesion was observed in the left occipital region with homogeneous contrast enhancement, suggestive for a meningioma, which was confirmed on magnetic resona...
CONCLUSION: Carbon-11-choline PET was found have a greater correlation with Gleason score than DWI and is considered to be more useful to predict a higher score in patients with prostate cancer. Fluorine-18-FDG PET was limited because of low sensitivity. PMID: 32222730 [PubMed - as supplied by publisher]
The diagnostic performance of 18F-sodium fluoride positron emission tomography/computed tomography (PET/CT) (NaF), 18F-fluorocholine PET/CT (FCH) and diffusion-weighted whole-body magnetic resonance imaging (DW-M...