Fluoroquinolone prophylaxis is highly effective for the prevention of central line-associated bloodstream infections in autologous stem cell transplant patients

Over the past decade, rates of central line-associated bloodstream infections (CLABSIs) have been reduced by over 50% among hospitalized patients through the implementation of standardized infection prevention strategies. [1,2] However, CLABSIs remain common in patients with hematologic malignancy and are associated with significant morbidity and mortality, including an increased risk of acute graft-versus host disease (GVHD), prolonged lengths of stay, and up to a 7-fold increased risk of death.

Source: Biology of Blood and Marrow Transplantation - November 24, 2018 Category: Hematology Authors: Matthew Ziegler, Daniel Landsburg, David Pegues, Warren Bilker, Cheryl Gilmar, Colleen Kucharczuk, Theresa Gorman, Kristen Bink, Amy Moore, Rebecca Fitzpatrick, Edward A. Stadtmauer, Patricia Mangan, Kelly Kraus, Jennifer H. Han Source Type: research