TNF ‐α–TNFR signal pathway inhibits autophagy and promotes apoptosis of alveolar macrophages in coal worker's pneumoconiosis

Conclusion: TNF ‐α–TNFR signal pathway was involved in the occurrence and development of CWP by activating FAS–caspase‐8 and thus inhibiting autophagy while promoting apoptosis of AM.

Source: Journal of Cellular Physiology - November 23, 2018 Category: Cytology Authors: Qingzeng Qian, Xiangke Cao, Bin Wang, Yi Qu, Qingqiang Qian, Zhiqian Sun, Fumin Feng Tags: ORIGINAL RESEARCH ARTICLE Source Type: research