Relationship of DNA methylation to mutational changes and transcriptional organization in fusion ‐positive and fusion‐negative rhabdomyosarcoma

In conclusion, these findings highlight the interaction of epigenetic changes with mutational alterations and transcriptional organizati on in RMS tumors, and contribute to improved molecular categorization of these tumors.This article is protected by copyright. All rights reserved.

Source: International Journal of Cancer - November 22, 2018 Category: Cancer & Oncology Authors: Wenyue Sun, Bishwanath Chatterjee, Jack F. Shern, Rajesh Patidar, Young Song, Yonghong Wang, Robert L. Walker, Bruce R. Pawel, Corinne M. Linardic, Peter Houghton, Stephen M. Hewitt, Daniel C. Edelman, Javed Khan, Paul S. Meltzer, Frederic G Tags: Research Article Source Type: research