IL-17A Is Critical for CD8+ T Effector Response in Airway Epithelial Injury After Transplantation

Conclusions Our data reveal the critical role of IL-17A in mediating CD8+ T effector response that causes airway epithelial injury and lung allograft rejection, and indicate that inhibition of STAT3 signals could drive CD8+ T cells from Tc17 toward Tc1 development.
Source: Transplantation - Category: Transplant Surgery Tags: Original Basic Science—General Source Type: research