BPI Fold Containing Family A Member 1 (BPIFA1) regulates mucosal microbiota and basal Interferon signaling

Conclusion: BPIFA1 is important in maintaining basal microbiome and cytokine expression homeostasis in multiple mucosae. Disruption of this first line of mucosal host defense changes microbiota and IFN signaling that may modulate host-microbe interactions

Source: European Respiratory Journal - November 19, 2018 Category: Respiratory Medicine Authors: Britto, C., Khanal, S., Wu, B., Li, Y., Segal, L. Tags: Airway Cell Biology and Immunopathology Source Type: research