Local depletion of the recruitment of macrophages reduces acute lung injury in rats

Conclusion: Locally CCR2 or CCL2 blockade reduced infiltrated monocyte/macrophages into the lung, without affecting the systemic production. The reduction of CCR2+monocytes/macrophages was associated with a decrease of inflammation in the lung
Source: European Respiratory Journal - Category: Respiratory Medicine Authors: Tags: Mechanisms of Lung Injury and Repair Source Type: research