Onset of Musculoskeletal Adverse Events Varies Between Statins

MONDAY, Nov. 19, 2018 -- The onset of musculoskeletal adverse events (MAEs) during statin monotherapy is significantly faster with use of atorvastatin and rosuvastatin versus simvastatin, according to a study published online Nov. 7 in Pharmacology...
Source: Drugs.com - Pharma News - Category: Pharmaceuticals Source Type: news

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Source: The Journal of Thoracic and Cardiovascular Surgery - Category: Cardiovascular & Thoracic Surgery Authors: Source Type: research
Exclusive: NHS launching large trial of approach that could boost number of transplants and their success rateThousands of lives could be saved globally by giving patients a 10p statin before transplants, doctors have said, as the NHS launches the world ’s largest clinical trial in organ donors.The medical breakthrough is predicted to dramatically increase the supply of organs for transplant. Currently, demand for organs vastly exceeds the number available. Every year thousands of people die waiting for a transplant, including hundreds in Britain.Continue reading...
Source: Guardian Unlimited Science - Category: Science Authors: Tags: Organ donation Statins Medical research NHS Health Society Science UK news Source Type: news
Acute respiratory distress syndrome is a heterogenous syndrome with many etiologies for which there are no definitive pharmacologic treatments, despite decades of research. We explore some adjunctive pharmacologic therapies, including neuromuscular blockade, corticosteroids, and inhaled pulmonary vasodilators. Additionally, we explore some investigative therapies, including Vitamin C, beta-agonists, statins, mesenchymal stromal cells, and granulocyte –macrophage colony stimulating factor. We do discuss the potential role of steroids in acute respiratory distress syndrome with severe acute respiratory syndrome coronav...
Source: Critical Care Clinics - Category: Intensive Care Authors: Source Type: research
Our objective is to describe two genetically confirmed Oculopharyngeal Muscular Dystrophy (OPMD) patients with HMGCoARdase-antibody positive autoimmune necrotic myopathy (AINM) responsive to immunosuppressive treatment. Although clinicians have suspected muscular dystrophy patients are at increased risk of statin side-effects, to date no patients with genetically confirmed muscular dystrophy have been reported with HMGCoRdase-antibody positive AINM. Here we describe the clinical presentation, serology, muscle pathology and response to treatment in two patients with genetically confirmed OPMD who developed statin-associated AINM.
Source: Neuromuscular Disorders - Category: Neurology Authors: Source Type: research
STATINS are a group of medicines that can help lower the level of cholesterol in the blood. Satins can also be taken to prevent heart disease, including heart attacks and strokes. Now, a new study has found that the cheap pills may also help treat ulcerative colitis.
Source: Daily Express - Health - Category: Consumer Health News Source Type: news
In conclusion, patients undergoing statin treatment have a lower risk of developing RVO compared to patients not taking statins.
Source: International Journal of Environmental Research and Public Health - Category: Environmental Health Authors: Tags: Article Source Type: research
To evaluate the association between statin use and the risk of developing rheumatoid arthritis (RA) in a large, US case-control study.
Source: Arthritis Research and Therapy - Category: Rheumatology Authors: Tags: Research article Source Type: research
We aimed to determine the relationship between statin adherence measured directly, and by self-report measures and serum cholesterol levels.
Source: Atherosclerosis - Category: Cardiology Authors: Source Type: research
STATINS are a group of medicines that can help lower the level of cholesterol in the blood. However, with treatments like statins come side effects - the NHS warn that a skin rash with pink-red blotches, especially on the palms of the hands or soles of the feet could appear if you take statins.
Source: Daily Express - Health - Category: Consumer Health News Source Type: news
Background: Chronic kidney disease (CKD) is an increasingly prevalent disease state met with great morbidity and mortality primarily resulting from the high incidence of adverse cardiovascular outcomes. Therapeutic strategies in this patient population aim at controlling modifiable cardiovascular risk factors, including dyslipidemia.Summary: In this review article, we first provide the latest pathophysiologic evidence regarding the altered dyslipidemia pattern in CKD, followed by its contemporary management according to the latest guidelines. Moreover, we present the current progress regarding the emerging therapeutic stra...
Source: American Journal of Nephrology - Category: Neurology Source Type: research
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