Propofol attenuates inflammatory damage on neurons following cerebral infarction by inhibiting excessive activation of microglia.

In conclusion, propofol inhibited the excessive activation of microglia through the A2b receptor and attenuated the inflammatory injury following cerebral infarction. The current study may provide a reliable basis for further clinical studies on propofol and its putative role in improving the prognosis of patients with cerebral infarction. PMID: 30431058 [PubMed - as supplied by publisher]

https://www.ncbi.nlm.nih.gov/pubmed/30431058?dopt=Abstract

Source: International Journal of Molecular Medicine - November 5, 2018 Category: Molecular Biology Authors: Yu H, Wang X, Kang F, Chen Z, Meng Y, Dai M Tags: Int J Mol Med Source Type: research