Infectious skin disorders encountered in a pediatric emergency department of a tertiary care hospital in Argentina: a descriptive study

ConclusionOur data reveal the extremely high frequency of ISDs seen at the PED, underlying the need for closer cooperation between dermatologists and pediatricians.
Source: International Journal of Dermatology - Category: Dermatology Authors: Tags: Report Source Type: research

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Publication date: Available online 21 October 2019Source: Nanomedicine: Nanotechnology, Biology and MedicineAuthor(s): Wesley L. Fotoran, Thomas Müntefering, Nicole Kleiber, Beatriz N.M. Miranda, Eva Liebau, Darrell J. Irvine, Gerhard WunderlichAbstractLipid particles for drug delivery can be modified to create multilayer vesicles with higher stability and improved cargo interaction. Here, we used lipids capable of forming hydrogen bonds instead of covalent bonds and designed stable vesicles-inside-vesicles with a high capacity of entrapping antimalarial drugs such as chloroquine (hydrophilic) and Artemisinin (lipophi...
Source: Nanomedicine: Nanotechnology, Biology and Medicine - Category: Nanotechnology Source Type: research
Conclusion: Chicago sky blue and Calcofluor white staining are excellent methods for diagnosis of fungal infections, including those that cannot be confirmed using conventional methods. PMID: 31632123 [PubMed]
Source: Clinical, Cosmetic and Investigational Dermatology - Category: Dermatology Tags: Clin Cosmet Investig Dermatol Source Type: research
ConclusionHepatitis C presents a high burden of disease in the countries under study, and its management imposes significant costs on health systems.ResumenObjetivoLa infección crónica por el virus de la hepatitis C (VHC) es una de las principales causas de cirrosis y carcinoma hepatocelular (CHC) en el mundo. El objetivo fue describir la epidemiología, el consumo de recursos y los costos relevantes en el manejo de la hepatitis C en cuatro países latinoamericanos: Argentina, Colombia, Uruguay y Venezuela.Diseño del estudioRevisión bibliográfica, estudio de costos y opini&oac...
Source: Value in Health Regional Issues - Category: International Medicine & Public Health Source Type: research
Authors: Davidson L, Knight J, Bowen AC Abstract Impetigo, scabies, cellulitis and abscesses are common in Australian Aboriginal children. These conditions adversely affect wellbeing and are associated with serious long term sequelae, including invasive infection and post-infectious complications, such as acute post-streptococcal glomerulonephritis and acute rheumatic fever, which occurs at the highest documented rates in the world in remote Aboriginal communities. Observational research in remote communities in northern Australia has demonstrated a high concurrent burden of scabies and impetigo and their post-infe...
Source: Medical Journal of Australia - Category: General Medicine Tags: Med J Aust Source Type: research
Natália F. Martins Root-knot nematodes (RKN), from the Meloidogyne genus, have a worldwide distribution and cause severe economic damage to many life-sustaining crops. Because of their lack of specificity and danger to the environment, most chemical nematicides have been banned from use. Thus, there is a great need for new and safe compounds to control RKN. Such research involves identifying beforehand the nematode proteins essential to the invasion. Since G protein-coupled receptors GPCRs are the target of a large number of drugs, we have focused our research on the identification of putative nematode GPCRs ...
Source: Molecules - Category: Chemistry Authors: Tags: Article Source Type: research
Conclusions: Naturally acquired sexual stage immunity, as detected by antibodies to Pfs230 and Pfs48/45, was present in most studies analyzed. Significant between-study heterogeneity was seen, and methodological factors were a major contributor to this, and prevented further analysis of epidemiological and biological factors. This demonstrates a need for standardized protocols for conducting and reporting seroepidemiological analyses.
Source: Frontiers in Immunology - Category: Allergy & Immunology Source Type: research
AbstractA major advance in antimalarial drug discovery has been the shift towards cell-based phenotypic screening, with notable progress in the screening of compounds against the asexual blood stage, liver stage, and gametocytes. A primary method for drug target deconvolution inPlasmodium falciparum is in vitro evolution of compound-resistant parasites followed by whole-genome scans. Several of the most promising antimalarial drug targets, such as translation elongation factor 2 (eEF2) and phenylalanine tRNA synthetase (PheRS), have been identified or confirmed using this method. One drawback of this method is that if a mu...
Source: Genome Medicine - Category: Genetics & Stem Cells Source Type: research
Publication date: Available online 20 October 2019Source: The LancetAuthor(s): Daniel I Sessler, Lijian Pei, Yuguang Huang, Edith Fleischmann, Peter Marhofer, Andrea Kurz, Douglas B Mayers, Tanja A Meyer-Treschan, Martin Grady, Ern Yu Tan, Sabry Ayad, Edward J Mascha, Donal J Buggy, Gang Tan, Zhiyong Zhang, Helen Keane, Maurice Stokes, Oliver Zotti, Michael Gnant, Silvia Perez-ProttoSummaryBackgroundThree perioperative factors impair host defence against recurrence during cancer surgery: the surgical stress response, use of volatile anaesthetic, and opioids for analgesia. All factors are ameliorated by regional anaesthesia...
Source: The Lancet - Category: General Medicine Source Type: research
Publication date: December 2019Source: Molecular Immunology, Volume 116Author(s): Bijara Devi Sanasam, Sanjeev KumarAbstractMalaria caused by Plasmodium falciparum is the most deadly and a major health issue worldwide. In spite of several control programs, there hasn’t been much improvement in keeping the disease under control. The appearance of drug resistant strains of Plasmodium in addition to insecticide resistance of the Anopheles vector has been a hurdle. Therefore, it is highly desirable to identify new potential candidates that can be targeted for therapeutic intervention. The present study identifies AMR1, a...
Source: Molecular Immunology - Category: Allergy & Immunology Source Type: research
This week's case was generously donated by Professor Agnes Kurniawan from the University of Indonesia. The following motile structure was reported to emerge from the anus of a man from rural Indonesia. He had no other gastrointestinal symptoms.You can see its subtle movement here:This structure was expressed from the submitted object:Identification?
Source: Creepy Dreadful Wonderful Parasites - Category: Parasitology Source Type: blogs
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