Structural basis for anthrax toxin receptor 1 recognition by Seneca Valley Virus [Microbiology]

Recently, the use of oncolytic viruses in cancer therapy has become a realistic therapeutic option. Seneca Valley Virus (SVV) is a newly discovered picornavirus, which has earned a significant reputation as a potent oncolytic agent. Anthrax toxin receptor 1 (ANTXR1), one of the cellular receptors for the protective antigen secreted...

Source: Proceedings of the National Academy of Sciences - November 13, 2018 Category: Science Authors: Nadishka Jayawardena, Laura N. Burga, Richard A. Easingwood, Yoshimasa Takizawa, Matthias Wolf, Mihnea Bostina Tags: PNAS Plus Source Type: research