Elevated IL-33 promotes expression of MMP2 and MMP9 via activating STAT3 in alveolar macrophages during LPS-induced acute lung injury.

Conclusion: The IL-33/STAT3/MMP2/9 regulatory pathway is activated in alveolar macrophages during acute lung injury, which may exacerbate the pulmonary inflammation. PMID: 30410547 [PubMed - in process]

https://www.ncbi.nlm.nih.gov/pubmed/30410547?dopt=Abstract

Source: Cellular and Molecular Biology Letters - November 10, 2018 Category: Biochemistry Authors: Liang Y, Yang N, Pan G, Jin B, Wang S, Ji W Tags: Cell Mol Biol Lett Source Type: research

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