SGLT2 inhibitor regulates ketone body metabolism via inter ‐organ crosstalk

ConclusionsSGLT2i increased systemic and tissue BHB levels by upregulating ketogenic enzymes and transporters in the liver, kidney, and intestine, suggesting the integrated physiological consequences in ketone body metabolism by SGLT2i administration.This article is protected by copyright. All rights reserved.

Source: Diabetes, Obesity and Metabolism - November 8, 2018 Category: Endocrinology Authors: Jin Hee Kim, Minyoung Lee, Soo Hyun Kim, So Ra Kim, Byung ‐Wan Lee, Eun Seok Kang, Bong‐Soo Cha, Jin Won Cho, Yong‐ho Lee Tags: ORIGINAL ARTICLE Source Type: research