Microvessels may Confound the “Swallow Tail Sign” in Normal Aged Midbrains: A Postmortem 7 T SW‐MRI Study

CONCLUSIONBoth iron deposits and microvessels contribute to the hyposignal surrounding nigrosome 1 in susceptibility weighted imaging of normal aged midbrains at ultrahigh ‐field strength. When assessing the substantia nigra for the presence or absence of the “swallow tail sign,” intrinsic vessels may be a sporadic confounder.
Source: Journal of Neuroimaging - Category: Radiology Authors: Tags: Short Communication Source Type: research

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AbstractPurposeThe aim of this study was to assess patients with Parkinson ’s disease (PD) in comparison with patients without PD for the treatment of hip fractures. Therefore, we performed a mono-centre study including 145 patients with PD and 2135 consecutive patients without PD as a concurrent group (C).MethodsFor analysis, we used our database, in which any type of hip fracture was enrolled. The study period ranged from 2007 to 2017, and the patient age was  ≥ 60 years. Overall, 10 variables were included. The primary measures were operations for any reason, infection, dislocation, failure, ...
Source: European Journal of Orthopaedic Surgery and Traumatology - Category: Orthopaedics Source Type: research
Conditions:   Freezing of Gait;   Parkinson Disease Intervention:   Device: Tactile Cueing Device Sponsors:   Swiss Federal Institute of Technology;   Rehaklinik Zihlschlacht AG Not yet recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Conditions:   Parkinson Disease;   Idiopathic Parkinson Disease Interventions:   Dietary Supplement: N acetyl cysteine;   Drug: [F-18] Fluorodopa Positron Emission Tomography Sponsor:   Thomas Jefferson University Active, not recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
PARKINSON'S disease symptoms develop slowly over a long time, and could be caused by nerve damage in the brain. You could lower your risk of the brain condition's signs by making some diet swaps. This is the best fruit you should add to your breakfast routine to avoid Parkinson's symptoms.
Source: Daily Express - Health - Category: Consumer Health News Source Type: news
This week, I’m in conversation with prize-winning fantasy author Elizabeth Hopkinson. Elizabeth is a writer of fairy tales and her latest project is an anthology called Asexual Fairy Tales. She previously joined me on the Thursday Throng in 2013 with her first novel, Silver Hands. Elizabeth is from Bradford, West Yorkshire (UK), home of the Bronte sisters and the Cottingley Fairies.  She loves the 18th century, Japan, mocha, and finding the magical in the ordinary. Elizabeth’s short fiction has appeared in numerous publications, and she has won prizes including the James White Award, Fairytalez Best New Ta...
Source: The Hysterectomy Association - Category: OBGYN Authors: Tags: Podcast Writing author interview crowdfunding Source Type: news
(Purdue University) SpeechVive Inc. announced Tuesday (July 7) the completion of a convertible note that will provide the necessary resources to begin scaling the business. SpeechVive is a Purdue University-affiliated medical device company dedicated to treating the speech conditions of over 1.5 million people in the United States who suffer from chronic neurological diseases, such as Parkinson's disease.
Source: EurekAlert! - Medicine and Health - Category: International Medicine & Public Health Source Type: news
The steady increase in life-expectancy of world population, coupled to many genetic and environmental factors (for instance, pre- and post-natal exposures to environmental neurotoxins), predispose to the onset of neurodegenerative diseases, whose prevalence is expected to increase dramatically in the next years. Recent studies have proposed links between the gut microbiota and neurodegenerative disorders such as Alzheimer's and Parkinson's diseases. Human body is a complex structure where bacterial and human cells are almost equal in numbers, and most microbes are metabolically active in the gut, where they potentially inf...
Source: Frontiers in cellular and infection microbiology - Category: Microbiology Source Type: research
Mucosal Immunology, Published online: 07 July 2020; doi:10.1038/s41385-020-0318-2IL-17A both initiates, via IFNγ suppression, and limits the pulmonary type-2 immune response to nematode infection
Source: Mucosal Immunology - Category: Allergy & Immunology Authors: Source Type: research
Yi Xu Environmental lead (Pb) exposure is closely associated with pathogenesis of a range of neurological disorders, including Alzheimer’s disease (AD), Parkinson’s disease (PD), amyotrophic lateral sclerosis (ALS), attention deficit/hyperactivity disorder (ADHD), etc. Epigenetic machinery modulates neural development and activities, while faulty epigenetic regulation contributes to the diverse forms of CNS (central nervous system) abnormalities and diseases. As a potent epigenetic modifier, lead is thought to cause neurological disorders through modulating epigenetic mechanisms. Specifically, incre...
Source: International Journal of Environmental Research and Public Health - Category: Environmental Health Authors: Tags: Review Source Type: research
People living with Parkinson's disease (PwP) experience a wide range of motor and non-motor symptoms associated with increasing complexity of care delivery. A multispecialty approach has been presented as an intuitive solution for tailored and comprehensive care delivery. Nevertheless, past trials of both multidisciplinary or interdisciplinary care models in PD suggested no measurable change to a small benefit in quality of life (QoL) and failed to show economic sustainability. We propose a home-based community-centred integrated care (iCARE-PD) for PwP as a pragmatic solution to harness the potential of existing care reso...
Source: Parkinsonism and Related Disorders - Category: Neurology Authors: Tags: Point of view Source Type: research
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