Zoonotic disease research in East Africa

The East African region is endemic with multiple zoonotic diseases and is one of the hotspots for emerging infectious zoonotic diseases with reported multiple outbreaks of epidemic diseases such as Ebola, Marb...
Source: BMC Infectious Diseases - Category: Infectious Diseases Authors: Tags: Research article Source Type: research

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An outbreak of a new coronavirus in China has spread to more cities, Chinese authorities said on Monday, as the number of patients tripled and a third person died, stoking concerns about containment of the illness.
Source: Reuters: Health - Category: Consumer Health News Tags: healthNews Source Type: news
Chinese authorities and the World Health Organization (WHO) say a new strain of coronavirus is behind the outbreak of pneumonia in the central city of Wuhan, which has erupted just ahead of the Lunar New Year, the country's biggest festival.
Source: Reuters: Health - Category: Consumer Health News Tags: healthNews Source Type: news
China's agriculture minister urged authorities to prevent a recurrence in African swine fever outbreaks, according to a statement on the ministry's website on Monday.
Source: Reuters: Health - Category: Consumer Health News Tags: healthNews Source Type: news
Publication date: Available online 18 January 2020Source: International Journal for Parasitology: Parasites and WildlifeAuthor(s): Serene Yu, Joseph Modarelli, John M. Tomeček, Justin T. French, Clayton Hilton, Maria D. Esteve-GasentAbstractDetermining which wildlife hosts are involved in the enzootic cycles of tick-borne diseases (TBD) enables enhanced surveillance and risk assessment of potential transmission to humans and domestic species. Currently, there is limited data to indicate which tick-borne pathogens (TBP) can infect coyotes. Additionally, limited surveillance data for white-tailed deer (WTD) in south Texas i...
Source: International Journal for Parasitology: Parasites and Wildlife - Category: Parasitology Source Type: research
In this study, we established a continuous epithelial cell line, named PT cell, from the pig tonsil. This cell is susceptible to JEV. We determined the growth characteristics, molecular properties, microstructure profiles of PT cell. JEV is easy to enter PT cell which may partly explain the reason of persist infection. We further determined that LMAN2L, a mannose lectin proteins, is the primary viral receptors for JEV entry in PT cell. IFITM3, an cellular surface antiviral factor, is underexpression in PT cell after JEV infection. All these results provide solid evidence that PT cell will promote additional research on JEV...
Source: Veterinary Microbiology - Category: Veterinary Research Source Type: research
Generet prize will fund more trials by Steven Laureys to help written-off ‘vegetative’ patientsA pioneering Belgian neurologist has been awarded €1m to fund further work in helping diagnose the most severe brain injuries, as he seeks to battle “the silent epidemic” and help people written off as “vegetative” who, it is believed, will never recover.Steven Laureys, head of the coma science group at Li ège University hospital, plans to use the £850,000 award –larger than the Nobel prize– to improve the diagnosis of coma survivors labelled as being in a “p...
Source: Guardian Unlimited Science - Category: Science Authors: Tags: Neuroscience Belgium Europe Medical research Source Type: news
AbstractPurpose of ReviewThe childhood obesity epidemic is widely considered to have reached pandemic proportions. Across the world, children with obesity are facing numerous psychological and physiological issues that follow them into adulthood, frequently leading to chronic illness and early death. In an effort to combat the compounding effects of childhood overweight, researchers are attempting to identify biological and environmental contributors to child weight. Parenting styles are one recognized influence on child diet and body mass index (BMI). This review is a comprehensive examination of the literature on the inf...
Source: Current Nutrition Reports - Category: Nutrition Source Type: research
Background and Rationale Ebola virus disease (EVD) is a rare but deadly and highly contagious zoonotic infection first recognized in 1976 in rural Central Africa.1,2 Though associated with high mortality, the remote locations characterized by low population density of these early outbreaks, curtailed extensive exposure.1 In stark contrast, the 2014 EVD outbreaks in West Africa (Guinea, Liberia, and Sierra Leone) occurred primarily in urban areas. 1,23 Widespread morbidity and mortality are associated with the hemorrhagic fever caused by the virus. An unprecedented number of cases (>28,600) were reported since the first ...
Source: PLOS Currents Outbreaks - Category: Epidemiology Authors: Source Type: research
Publication date: Available online 12 October 2017 Source:The Lancet Author(s): David M Pigott, Aniruddha Deshpande, Ian Letourneau, Chloe Morozoff, Robert C Reiner, Moritz U G Kraemer, Shannon E Brent, Isaac I Bogoch, Kamran Khan, Molly H Biehl, Roy Burstein, Lucas Earl, Nancy Fullman, Jane P Messina, Adrian Q N Mylne, Catherine L Moyes, Freya M Shearer, Samir Bhatt, Oliver J Brady, Peter W Gething, Daniel J Weiss, Andrew J Tatem, Luke Caley, Tom De Groeve, Luca Vernaccini, Nick Golding, Peter Horby, Jens H Kuhn, Sandra J Laney, Edmond Ng, Peter Piot, Osman Sankoh, Christopher J L Murray, Simon I Hay Background Predictin...
Source: The Lancet - Category: General Medicine Source Type: research
We agree with the Claire Tully and colleagues'1 excellent summary of therapeutic and preventive strategies for Ebola. For long-term strategies, multipathogen (multivalent) vaccines or therapeutic vaccines should be considered. With the implementation of vaccines and public health measures, this outbreak will probably be contained, but the social and economic burden for west Africa will persist long after this epidemic. A substantial risk of Ebola virus disease becoming endemic or re-emerging for another zoonotic transmission event exists.
Source: The Lancet Infectious Diseases - Category: Infectious Diseases Authors: Tags: Correspondence Source Type: research
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