Bacterial genotoxin colibactin promotes colon tumour growth by inducing a senescence-associated secretory phenotype

Conclusion
These data reveal a new paradigm for carcinogenesis, in which colibactin-induced senescence has an important role.

Source: Gut - October 31, 2014 Category: Gastroenterology Authors: Cougnoux, A., Dalmasso, G., Martinez, R., Buc, E., Delmas, J., Gibold, L., Sauvanet, P., Darcha, C., Dechelotte, P., Bonnet, M., Pezet, D., Wodrich, H., Darfeuille-Michaud, A., Bonnet, R. Tags: Colon cancer Source Type: research