Establishment of a rapid and footprint-free protocol for differentiation of human embryonic stem cells into pancreatic endocrine cells with synthetic mRNAs encoding transcription factors

Transplantation of pancreatic β cells generated in vitro from pluripotent stem cells (hPSCs) such as embryonic stem cells (ESCs) or induced pluripotent stem cells (iPSCs) has been proposed as an alternative th...

Source: Stem Cell Research and Therapy - October 25, 2018 Category: Stem Cells Authors: Hideomi Ida, Tomohiko Akiyama, Keiichiro Ishiguro, Sravan K. Goparaju, Yuhki Nakatake, Nana Chikazawa-Nohtomi, Saeko Sato, Hiromi Kimura, Yukihiro Yokoyama, Masato Nagino, Minoru S. H. Ko and Shigeru B. H. Ko Tags: Research Source Type: research