Validation of Numerical Simulations of Thoracic Aorta Hemodynamics: Comparison with In Vivo Measurements and Stochastic Sensitivity Analysis

ConclusionsIn summary, a successful integration of hemodynamic simulations and of MRI data for a patient-specific simulation has been shown. The wall compliance seems to have a significant impact on the numerical predictions; a larger wall elasticity generally improves the agreement with experimental data.
Source: Cardiovascular Engineering and Technology - Category: Cardiology Source Type: research

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ConclusionsThese results provide evidence that the impaired cognitive flexibility of OCD may be associated with dysfunctions of the brain network from the dorsal caudate (DC) to important nodes of the salience network. Our results extend the neuropsychological model of OCD by showing intrinsically different associations between OCD and HC in functional network and cognitive flexibility.
Source: NeuroImage: Clinical - Category: Radiology Source Type: research
Publication date: Available online 14 September 2019Source: European Journal of RadiologyAuthor(s): Thomas Sartoretti, Elisabeth Sartoretti, Michael Wyss, Árpád Schwenk, Luuk van Smoorenburg, Barbara Eichenberger, Arash Najafi, Christoph Binkert, Anton S. Becker, Sabine Sartoretti-ScheferAbstractPurposeTo compare image quality between a 2D T1w turbo spin echo (TSE) sequence and a Compressed SENSE accelerated 3D T1w black blood TSE sequence (equipped with a black blood prepulse for blood signal suppression) in pre- and postcontrast imaging of the pituitary and to assess scan time reductions.Methods and Materia...
Source: European Journal of Radiology - Category: Radiology Source Type: research
Publication date: Available online 14 September 2019Source: Brain, Behavior, and ImmunityAuthor(s): Silke Kreitz, Alice Zambon, Marianne Ronovsky, Lubos Budinsky, Thomas H. Helbich, Spyros Sideromenos, Claudiu Ivan, Laura Konerth, Isabel W., Angelika Berger, Arnold Pollak, Andreas Hess, Daniela D. PollakAbstractGestational infection constitutes a risk factor for the occurrence of psychiatric disorders in the offspring. Activation of the maternal immune system (MIA) with subsequent impact on the development of the fetal brain is considered to form the neurobiological basis for aberrant neural wiring and the psychiatric mani...
Source: Brain, Behavior, and Immunity - Category: Neurology Source Type: research
This study aimed to describe patellar calcar morphometry by knee MRI and develop a 3D reconstruction software-assisted.Materials and methodsConsecutive adult patients, submitted to knee MRI, between 2014 and 2017, were entered in IMPAX software. Exclusion criteria are history of patellar surgical intervention, trauma, chondromalacia, bone edema or bipartite patella. All MRI images were retrospectively reviewed by three readers. MRI patellar calcar measurements are height, width, thickness and posterior distance. 3D model protocol reconstruction: 3D Slicer software was used to design a preliminary model for each patient, an...
Source: Surgical and Radiologic Anatomy - Category: Anatomy Source Type: research
ConclusionBased on IVIM analysis, cerebral microvascular structure and function showed no difference between hypertensive and normotensive patients with moderate-to-severe OSA treated with CPAP. Treatment adherence with antihypertensive drug regime and, in turn, controlled hypertension seems not to affect microvascular structure and perfusion of the brain.Trial registrationClinicalTrials.gov Identifier: NCT02493673
Source: Neuroradiology - Category: Radiology Source Type: research
ConclusionsMinimal deviation adenocarcinoma represents one of rare cervical adenocarcinomas without HPV-association. While it is crucial to differentiate benign from malignant lesions in this subtype, imaging characteristics often overlap and may not provide a specific diagnosis. Therefore, it should be considered in suspicious multicystic cervical lesions and inconclusive PAP-smear. Definitive diagnosis of this subtype should be based on cervical biopsy.
Source: Archives of Gynecology and Obstetrics - Category: OBGYN Source Type: research
This study evaluates two methods for effective connectivity analysis, symbolic transfer entropy (STE) and vector autoregression (VAR), by applying them to TMS-EEG data. In terms of the consistency of results from different experimental sessions, STE is found to yield robust results irrespective of sessions, whereas VAR produces less correlation between sessions. Furthermore, STE preferentially detects the directional information flow from the TMS target. Taken together, our results suggest that STE is a reliable method for detecting the effect of TMS, implying that it would also be useful for identifying neural activity du...
Source: Neuroscience Research - Category: Neuroscience Source Type: research
Authors: Zelena D, Menant O, Andersson F, Chaillou E Abstract The periaqueductal gray (PAG) is less referred in relationship with emotions than other parts of the brain (e.g. cortex, thalamus, amygdala), most probably because of the difficulty to reach and manipulate this small and deeply lying structure. After defining how to evaluate emotions, we have reviewed the literature and summarized data of the PAG contribution to the feeling of emotions focusing on the behavioral and neurochemical considerations. In humans, emotions can be characterized by three main domains: the physiological changes, the communicative e...
Source: Endocrine Regulations - Category: Endocrinology Tags: Endocr Regul Source Type: research
Authors: Ozaki T, Kinoshita M, Arita H, Kagawa N, Fujimoto Y, Kanemura Y, Sakai M, Watanabe Y, Nakanishi K, Shimosegawa E, Hatazawa J, Kishima H Abstract Brain Tumor Image Analysis (BraTumIA) is a fully automated segmentation tool dedicated to detecting brain tumors imaged by magnetic resonance imaging (MRI). BraTumIA has recently been applied to several clinical investigations; however, the validity of this novel method has not yet been fully examined. The present study was conducted to validate the quality of tumor segmentation with BraTumIA in comparison with results from 11C-methionine positron emission tomogra...
Source: Oncology Letters - Category: Cancer & Oncology Tags: Oncol Lett Source Type: research
This study compared the diagnostic value of molybdenum target and dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) in different types of breast cancer. A retrospective analysis was performed on 120 female patients with breast cancer admitted to The First Affiliated Hospital of Zhengzhou University from February 2015 to October 2017. All of them underwent DCE-MRI and molybdenum target examination. Postoperatively, the pathological tissues were examined to determine their molecular typing. The sensitivity and diagnostic coincidence rates of Luminal-B breast cancer with different molecular types diagnosed by mol...
Source: Oncology Letters - Category: Cancer & Oncology Tags: Oncol Lett Source Type: research
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