Reward and executive control network resting-state functional connectivity is associated with impulsivity during reward-based decision making for cocaine users

Addiction is characterized by impulsive decision making that can lead to harmful long-term consequences (Verdejo-Garcia et al., 2018). The progression from controlled, voluntary drug use to compulsive drug taking has been described as a shift from flexible prefrontal cortical control to automatic responding driven by corticostriatal circuitry (Everitt et al., 2008). The brain circuits that are implicated in addiction comprise several intrinsic functional neural networks that coordinate decision-making and learning (Laird et al., 2011; Ma et al., 2015).

Source: Drug and Alcohol Dependence - October 24, 2018 Category: Addiction Authors: Andr éa L. Hobkirk, Ryan P. Bell, Amanda V. Utevsky, Scott Huettel, Christina S. Meade Tags: Full length article Source Type: research