A Rare Etiology of Severe Thrombocytopenia in Patient with Chronic Liver Disease.

A Rare Etiology of Severe Thrombocytopenia in Patient with Chronic Liver Disease. J Assoc Physicians India. 2018 Mar;66(3):81-82 Authors: Ansari MZ, Tolstoy R, Jagadeeswaran G Abstract Thrombocytopenia is a common complication in patients with chronic liver disease and is multi-factorial. It complicates the management and worsens the prognosis. Treatment options are costly and include platelet transfusion, splenectomy, splenic artery embolization, TIPPS and thrombopoietin (TPO) agonists. Here we are presenting a patient with decompensated liver disease with known chronic alcoholism and profound thrombocytopenia despite multiple platelet transfusions. On further work up we found a coexistent autoimmune etiology. Thrombocytopenia promptly responded to steroids, a cost effective option. PMID: 30341879 [PubMed - in process]
Source: Journal of the Association of Physicians of India - Category: General Medicine Tags: J Assoc Physicians India Source Type: research