Agreement between TOAST and CCS ischemic stroke classification: The NINDS SiGN Study

Conclusion:
Agreement between TOAST and CCS diagnoses was moderate. Caution is warranted when comparing or combining results based on the 2 systems. Replication of study results, for example, genome-wide association studies, should utilize phenotypes determined by the same classification system, ideally applied in the same manner.

Source: Neurology - October 27, 2014 Category: Neurology Authors: McArdle, P. F., Kittner, S. J., Ay, H., Brown, R. D., Meschia, J. F., Rundek, T., Wassertheil-Smoller, S., Woo, D., Andsberg, G., Biffi, A., Brenner, D. A., Cole, J. W., Corriveau, R., de Bakker, P. I. W., Delavaran, H., Dichgans, M., Grewal, R. P., Gwinn Tags: All Cerebrovascular disease/Stroke, All epidemiology ARTICLE Source Type: research