Apparent diffusion coefficients measured using different regions of interest in differentiating borderline from malignant ovarian tumors.

Apparent diffusion coefficients measured using different regions of interest in differentiating borderline from malignant ovarian tumors. Acta Radiol. 2018 Oct 18;:284185118805272 Authors: Lu JJ, Pi S, Ma FH, Zhang GF, Wei Qiang J Abstract Background Apparent diffusion coefficients (ADCs) measured using different regions of interest (ROIs) are widely used in differentiating ovarian tumors. Purpose To evaluate the diagnostic performance of ADCs with different ROIs in differentiating borderline ovarian tumors (BOTs) from malignant ovarian tumors (MOTs). Material and Methods Thirty-five BOTs and 54 MOTs who underwent diffusion-weighted magnetic resonance imaging (MRI) were evaluated retrospectively. ADC values were independently measured using five ROI methods: round; rectangle; hot-spot; edge drawing; and five sample ROIs. The inter- and intraclass correlation coefficients (ICCs), one-way analysis of variance, receiver operating characteristic curve analysis, and unpaired t-tests were used to perform the statistical analyses. Results The measurement reproducibility of the minimum ADC and mean ADC values were good or excellent for BOTs and MOTs (ICC = 0.70-0.95). The minimum and mean ADC value by the edge drawing ROI were significantly higher than those of the other ROI methods (both P 
Source: Acta Radiologica - Category: Radiology Authors: Tags: Acta Radiol Source Type: research

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Source: Frontiers in Oncology - Category: Cancer & Oncology Source Type: research
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Source: European Journal of Radiology - Category: Radiology Source Type: research
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Source: Journal of Magnetic Resonance Imaging - Category: Radiology Authors: Tags: Original Research Source Type: research
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Source: Journal of Magnetic Resonance Imaging - Category: Radiology Authors: Tags: Original Research Source Type: research
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