AFF3 upregulation mediates tamoxifen resistance in breast cancers.

CONCLUSIONS: These studies establish AFF3 as a key mediator of estrogen-independent growth and tamoxifen resistance and as a potential novel diagnostic and therapeutic target. PMID: 30326937 [PubMed - in process]

https://www.ncbi.nlm.nih.gov/pubmed/30326937?dopt=Abstract

Source: Clinical Genitourinary Cancer - October 16, 2018 Category: Cancer & Oncology Authors: Shi Y, Zhao Y, Zhang Y, AiErken N, Shao N, Ye R, Lin Y, Wang S Tags: J Exp Clin Cancer Res Source Type: research