Effects of Antioxidant Tempol on Systematic Inflammation and Endothelial Apoptosis in Emphysematous Rats Exposed to Intermittent Hypoxia.

CONCLUSION: Synergistic effects of IH with cigarette smoke-induced emphysema produce a greater inflammatory status and endothelial apoptosis. OS-related inflammation and endothelial cell apoptosis may play important roles in promoting cardiovascular dysfunction, and antioxidant tempol could achieve a partial protective effect.
PMID: 30328323 [PubMed - in process]

Source: Yonsei Medical Journal - October 18, 2018 Category: Universities & Medical Training Authors: Zhao H, Zhao Y, Li X, Xu L, Jiang F, Hou W, Dong L, Cao J Tags: Yonsei Med J Source Type: research