Contraception for Women with Epilepsy

AbstractPurpose of ReviewThe purpose of this review is to summarize the current available literature on contraception for women with epilepsy, and to provide recommendations for women with epilepsy on enzyme-inducing anti-seizure drugs and on non-enzyme-inducing anti-seizure drugs.Recent FindingsA recent study has confirmed the safety of the levonorgestrel-containing intrauterine device for women with epilepsy, with no effect on seizure control or anti-seizure drug levels. Other recent studies have found low serum etonogestrel or levonorgestrel levels in women on enzyme-inducing anti-seizure drugs and the etonogestrel or levonorgestrel implant, making this an unsuitable method for women on such drugs.SummaryWomen with epilepsy have an especially compelling need to avoid unplanned pregnancy, as some common anti-seizure medications have teratogenic or detrimental neurocognitive effects on exposed children. Women on enzyme-inducing anti-seizure drugs and their physicians must be particularly aware of drug interactions with hormonal contraceptive methods.

Source: Current Obstetrics and Gynecology Reports - October 17, 2018 Category: OBGYN Source Type: research