Proinsulin C-peptide is an autoantigen in people with type 1 diabetes [Immunology and Inflammation]
Type 1 diabetes (T1D) is an autoimmune disease in which insulin-producing beta cells, found within the islets of Langerhans in the pancreas, are destroyed by islet-infiltrating T cells. Identifying the antigenic targets of beta-cell reactive T cells is critical to gain insight into the pathogenesis of T1D and develop antigen-specific...
Source: Proceedings of the National Academy of Sciences - Category: Science Authors: Michelle So, Colleen M. Elso, Eleonora Tresoldi, Miha Pakusch, Vimukthi Pathiraja, John M. Wentworth, Leonard C. Harrison, Balasubramanian Krishnamurthy, Helen E. Thomas, Christine Rodda, Fergus J. Cameron, Jacinta McMahon, Thomas W. H. Kay, Stuart I. Man Tags: Biological Sciences Source Type: research
More News: Academies | Allergy & Immunology | Autoimmune Disease | Diabetes | Diabetes Type 1 | Endocrinology | Insulin | Pancreas