Neonatal screening in the Czech Republic: increased prevalence of selected diseases in low birthweight neonates

Conclusion: Although the underlying mechanisms are not well understood, results can be hypothesized that LBW (respectively prematurity) may lead to the secondary and often transitory hypothyroidism while cystic fibrosis and LCHADD may manifest already prenatally and result into preterm birth and LBW.What is Known:• The percentage of low birthweight (LBW) neonates in the Czech Republic has been increasing.•Previously published studies reported positive association between LBW and congenital hypothyroidism and cystic fibrosis.What is New:• The association between LCHADD and LBW has not yet been described.• LBW can be the first manifestation of cystic fibrosis and LCHADD.
Source: European Journal of Pediatrics - Category: Pediatrics Source Type: research