Prognostic significance of p16 & p53 immunohistochemical expression in triple negative breast cancer.

Conclusion: On the basis of significant association of p53 over-expression with worse prognostic factors in triple negative breast cancer, therefore we suggest that more large scale studies are needed to validate this finding in loco-regional population. Moreover, high expression of p16 in triple negative breast cancer suggests a potential role of this biomarker in triple negative breast cancer pathogenesis which should be investigated with molecular based research in our population. PMID: 30305801 [PubMed]
Source: Clinical Breast Cancer - Category: Cancer & Oncology Authors: Tags: BMC Clin Pathol Source Type: research