Dopamine signals related to appetitive and aversive events in paradigms that manipulate reward and avoidability.

Dopamine signals related to appetitive and aversive events in paradigms that manipulate reward and avoidability.
Brain Res. 2018 Oct 06;:
Authors: Gentry RN, Schuweiler DR, Roesch MR
Abstract
Using environmental cues to acquire good and avoid harmful things is critical for survival. Rewarding and aversive outcomes both drive behavior through reinforcement learning and sometimes occur together in the environment, but it remains unclear how these signals are encoded within the brain and if signals for positive and negative reinforcement are encoded similarly. Recent studies demonstrate that the dopaminergic system and interconnected brain regions process both positive and negative reinforcement necessary for approach and avoidance behaviors, respectively. Here, we review these data with a special focus on behavioral paradigms that manipulate both expected reward and the avoidability of aversive events to reveal neural correlates related to value, prediction error encoding, motivation, and salience.
PMID: 30300635 [PubMed - as supplied by publisher]

Source: Brain Research - October 6, 2018 Category: Neurology Authors: Gentry RN, Schuweiler DR, Roesch MR Tags: Brain Res Source Type: research