Diverse Pathophysiological Processes Converge on Network Disruption in Mania

Bipolar disorders are common and severe but their pathophysiology is poorly understood and existing treatments are only partially effective and provoke significant side effects(Chen and Dilsaver, 1996; Kessler et al., 1999; Leverich et al., 2003; Perlis et al., 2006; Slama et al., 2004). Many previous studies have used functional magnetic resonance imaging (fMRI) in humans to understand bipolar pathophysiology at the network and circuit level. Fewer studies, however, have compared bipolar participants across different symptomatic states.

Source: Journal of Affective Disorders - October 9, 2018 Category: Neurology Authors: Ms Ivy Lee, Ms Ivy Lee Tags: Research paper Source Type: research