Clinicopathological and genomic comparisons between different histologic components in combined small cell lung cancer and non-small cell lung cancer

Lung cancer is the leading cause of cancer-related deaths worldwide [1 –3]. This disease is classified into 2 major histologic subgroups: non-small cell lung cancer (NSCLC), which comprises 85% of cases; and small cell lung cancer (SCLC), which comprises 15% of cases [1–3]. NSCLC is further divided into several histologic subtypes, including adenocarcinoma and squa mous cell carcinoma. Surgical resection is the treatment of choice for early-stage NSCLC; in contrast, systemic chemotherapy is considered the standard of care for patients with advanced-stage disease.

Source: Lung Cancer - October 8, 2018 Category: Cancer & Oncology Authors: Mong-Wei Lin, Kang-Yi Su, Te-Jen Su, Chia-Ching Chang, Jing-Wei Lin, Yi-Hsuan Lee, Sung-Liang Yu, Jin-Shing Chen, Min-Shu Hsieh Source Type: research