GammaKnife versus VMAT radiosurgery plan quality for many brain metastases.

GammaKnife versus VMAT radiosurgery plan quality for many brain metastases. J Appl Clin Med Phys. 2018 Oct 04;: Authors: Potrebko PS, Keller A, All S, Sejpal S, Pepe J, Saigal K, Kandula S, Sensakovic WF, Shridhar R, Poleszczuk J, Biagioli M Abstract The purpose of this work was to compare dose distributions between two radiosurgery modalities, single-isocenter volumetric modulated arc therapy (VMAT), and GammaKnife Perfexion (GK), in the treatment of a large number (≥7) of brain metastases. Twelve patients with 103 brain metastases were analyzed. The median number of targets per patient was 8 (range: 7-14). GK plans were compared to noncoplanar VMAT plans using both 6-MV flattening filter-free (FFF) and 10-MV FFF modes. Parameters analyzed included radiation therapy oncology group conformity index (CI), 12, 6, and 3 Gy isodose volumes (V12 Gy, V6 Gy, V3 Gy), mean and maximum hippocampal dose, and maximum skin dose. There were statistically significant differences in CI (2.5 ± 1.6 vs 1.6 ± 0.8 and 1.7 ± 0.9, P 
Source: Journal of Applied Clinical Medical Physics - Category: Physics Authors: Tags: J Appl Clin Med Phys Source Type: research

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