Co-crystal of Tramadol –Celecoxib in Patients with Moderate to Severe Acute Post-surgical Oral Pain: A Dose-Finding, Randomised, Double-Blind, Placebo- and Active-Controlled, Multicentre, Phase II Trial

ConclusionSignificant improvement in the benefit –risk ratio was observed for CTC (doses ≥ 100 mg) over tramadol and placebo in the treatment of acute pain following oral surgery.FundingLaboratorios del Dr. Esteve, S.A.U.

https://link.springer.com/10.1007/s40268-018-0235-y

Source: Drugs in R&D - June 1, 2018 Category: Drugs & Pharmacology Source Type: research