Direct oral anticoagulants for the treatment of venous thromboembolism in cancer patients: Potential for drug –drug interactions

Venous thromboembolism (VTE), comprising deep vein thrombosis and pulmonary embolism, is a complication frequently encountered in patients with cancer, and is a major cause of morbidity and mortality (Prandoni et al., 2002; Chew et al., 2006). Large cohort population studies indicate that patients with cancer have an average 4- to 7-fold higher risk of VTE than the general population (Walker et al., 2013; Cronin-Fenton et al., 2010). Numerous factors influence this increased risk, including patient-related factors (e.g.
Source: Critical Reviews in Oncology Hematology - Category: Cancer & Oncology Authors: Source Type: research